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Showing posts with label Good Blastocyst Rate (GBR). Show all posts
Showing posts with label Good Blastocyst Rate (GBR). Show all posts

Double stimulation (Duo-OPU)







 —  Continuous stimulation and oocyte retrieval during both the follicular and luteal phases of poor responders in IVF/ICSI programs can increase the obtained oocytes per menstrual cycle



Since the patients with diminished ovarian reserve could spend lots of time, energy, and money, on the multiple IVF treatments, the idea of double stimulation in a single cycle was developed. The following study is to compare the IVF outcomes obtained after single-stimulation (follicular phase stimulation) versus duoble stimulation (during both the follicular and luteal phases) in poor responders in IVF/ICSI programs.
Stork Fertility Center Stork Fertility Center Author

To have a second child? Preimplantation genetic screening is a good choice



"Excuse me, my oocyte pick-up is done,
 but my husband is still doing the sperm collection. Please tell him that I got to go."

She left in a rush, and I forgot to ask her name.






The day was as hasty as usual, scheduling for retrieval operations and gynecologic examinations. Every consultant at the counter of assisted reproductive technology (ART) department was busy for works, and I was checking the patients' ID and consent forms. 
Stork Fertility Center Stork Fertility Center Author

The secret of age—maternal age and embryo aneuploidy


The chromosomal abnormality (aneuploidy) rate increases with maternal age.
By analyzing with next-generation sequencing, more precise information can be obtained.

Preimplantation genetic screening (PGS) is an examination to screen the embryos with abnormal dosage of chromosomes (aneuploid) in the IVF realm, and it is strongly recommended to the women with advanced maternal age or undergoing recurrent miscarriage. By excluding the aneuploid embryo transfer, the success rate of IVF can be significantly improved.

Stork Fertility Center Stork Fertility Center Author

The clinical outcomes of donor oocyte bank

The benefits of Frozen Oocyte Bank

  1. We guarantee that the donor has stored at least 10 mature oocytes in our center. Also, these mature oocytes will be provided only for you and will not be shared by another couple.
  2. By using the most advanced vitrification technology, the average survival rate after thawing in our center is about 90%.
  3. The treatment is more flexible and based on your time. After we receive the permission from the government, we can thaw the oocytes and fertilize the egg right away!

According to our recent statistics, patients undergoing oocyte donation program have 50-60% chance of conception in average. The pregnancy rate and live birth rate of oocyte donation program are similar to the woman of using their own eggs at or below age of 35.


Our Achievement

The pregnancy rate and the live birth rate are highly relevant to the quality of oocytes and the age of oocyte retrival. According to the statistics of Health Promotion Administration (HPA), female fertility even plummets after age of 34.

Using oocytes from the donor is absolutely an additional option of happiness for couple who are eagering to become mother and dad in a short term.
Based on our statistics, oocyte donation program has great pregnancy rate (about 70%) and high live birth rates (nearly 50%).


Comparison between Frozen Embryo and Fresh Embryo

To preserve the oocyte, Stork Fertility Center performs highly efficient vitrification method published by Kuwayama et al. Based on our center’s statistics, frozen oocyte and embryo survival rates are 90% in average.

According to the recorded literature, the clinical pregnancy rates for frozen embryo transfers and fresh embryo transfers are comparable. Similar results have been obtained at the Center. The pregnancy rate for frozen embryo transfers has even surpassed that of fresh embryo transfers.
Frozen embryo transfer could be applied in women with irregular menstruation, asynchronous embryo development, or there’s further inspection needed.

Comparison between Fresh Oocyte and Frozen Oocyte Bank

As reported by our statistics, there is no significance between frozen oocyte program and fresh oocyte program including fertilization rates, good embryo rate, good blastocyst rate, clinical pregnancy rate and implantation rate. That is, vitrification method will not cause significant harm to the oocytes and embryos.



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Stork Fertility Center Stork Fertility Center Author

The clinical outcomes of donor sperm bank

The percentage of Stork Fertility Center sperm donation cycles to the total sperm donation cycles in Taiwan:


*The sky-blue bar represents the percentage of SFC oocyte donation cycle, and the sky-blue plus apricot represents the total oocyte donation cycles in Taiwan.


The clinical outcomes of embryo transfer in the donated-oocyte recipients:



* BT= blastocyst transfer
* FBT = frozen (and then thawed) blastocyst transfer
Stork Fertility Center Stork Fertility Center Author

IVF program in Stork Fertility Center




Hystereoscopy (H-scopy)and Cervical Bacteria Culture:

Uterine condition plays a crucial role for embryo implantation. H-scopy is better to be arranged on MC day 7 to 11, when the endometrial thickness would not affect the examination of uterus lining. Fasting is required for eight hours prior to H-scopy, because of anesthesia safety for the uterine polyps removal.

Cervical Bacteria Culture prevents infection or inflammation during embryo transfer going through female vagina. There are three tests included in the exam,




More info:
➤ Examinations before the transfer
Ready to My IVF program in Stork Fertility Center

Follicle stimulation It starts from the 3rd day of your menstrual cycle, and the specialist will prescribe the most adequate medications of human recombinant follicle-stimulating hormones based on your original ovarian status. When it comes close to the date of ovulation (commonly on MC day 14), ultrasound monitoring and serum hormone exams are required to provide the actual size and maturation progress of stimulated follicles for the specialist.

Caution: Herbal medicines and other medicines containing hormones are forbidden during stimulation, and they may affect the outcomes of stimulation.

Oocyte retrieval 
Through transvaginal ultrasound-guided probe, the oocyte-pickup needle aspirates the follicle and also removes the oocyte inside. The lab technician then check the existence and quality of oocyte under a microscope immediately. After removing the cover of cumulus cells, the maturity of oocyte is confirmed. Only the mature oocyte (MII) is able to be fertilized.





Ferilization and Fresh transfer/Cryopreservation
The mature oocyte is fertilized by the washed sperms either by direct insemination or intracytoplasmic sperm injection (ICSI). After culturing for 5 to 6 days in vitro, the best embryos are at blastocyst stage and ready to be transferred into the womb if the hormone levels and uterine condition are both appropriate. Otherwise, cryopreserving these blastocysts in the liquid nitrogen until your favorite transferred month is quite popular in recent IVF programs. Frozen-thawed blastocyst transfer (FBT) is more patient-friendly for the women with tight schedules or overseas customers.


Luteal Support
After transferring of the precious blastocyst into the womb, the specialist would prescribe suitable medications to maintain the steadiness of your endomerium. The implantation of embryo may happen during the 4th day to 7th day after transferring. The serum β-HCG could be detected after 14 days to check the pregnancy.

Cautions: Smoking, drinking and caffeine are forbidden after embryo transfer.
Stork Fertility Center Stork Fertility Center Author

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