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What is IUI?

IntraUterine Insemination/IUI

What is IUI?

Although many have heard the term “Artificial Reproduction” before, majority do not fully understand it. Actually, it is a relatively simple concept – collected sperm is prepared by utilizing Swim-up Technique, Density Gradient or Centrifugation with Washing to separate potentially fertile spermatozoa from immotile ones and remove any bacteria, debris, chemicals and seminal plasma. Preparation improves sperm’s motility, increasing its ability to penetrate the oocyte.

Only selected sperm, with high forward motility will be inseminated to induce pregancy.

Who are candidates for IUI?

Couples must be legally married and healthy. The wife should have a normal uterus/ ovary/ fallopian tubes and the husband should have quality sperm (high count, good forward motility). Couples experiencing any of the below problems can utilize IUI to assist conception:

1) Cervical mucus scarcity or cervical stenosis
2) Irregular sex life and/or sexual disorder
3) Still failed to conceive despite trying to get pregnant for six (6) months
4) Unexplained infertility
5) Male infertility: low quality spermatozoa such as low forward motility and quantity, abnormal morphology, etc.

Stork Fertility Center Stork Fertility Center Author

Should I do surgery for cyst removal?

Different sequential changes due to different mechanisms cuasing damage to the ovarian reserve

Menstrual pain, painful intercourse, and frequently lower abdominal pain are not unfamiliar to the women who are suffering with endometriosis. Besides this annoying pains, the problem of infertility is another agony. Endometriosis is one of primary infertility causes, especially if one or both ovaries are involved, and ovarian endometriomas are found in 20% of patients with endometriosis. The most common symptoms is so called as chocolate cyst, which is built up by menstrual blood over months and years and turned to brown color.

Ruptures of ovarian endometrioma are associated with pelvic adhesion and infections, so many patients would like to remove the cyst to alleviate pelvic pain or improve spontaneous fertility. However, the most effective treatment modality to endometrioma is still controversial. The postoperative safety to the ovarian function and the recurrence of the disease are two unsolved problems. In the published article of Fertility and Sterility Journal (2013), the group in department of obstetrics and gynecology, Nagoya university, has reported the statistical data of the endometrioma patients undertaking cystectomy. They analyzed the AMH levels of these patients before and after the surgery to evaluate the effect. The patients with bilateral cystectomy showed significant reduced AMH than that of patients with unilateral cystectomy,

AMH (ng/ml)a
Postoperative one month
Postoperative one year
a Anti-Müllerian hormone (AMH): The hormone is secreted by ovary and reflects the ovarian reserve. It is decreased with decreasing of remaining ovarian follicle count. 
b P-value < .05, statistic difference

Stork Fertility Center Stork Fertility Center Author