Stork Diary.
to Share Stork Life Events

The Most Important Choice in My Life



I am a woman who has gotten primary ovarian insufficiency, so I stopped having a menstrual cycle since I was in high school. I have to take pills to make my menstrual cycle regular. Thus, I started my infertility treatment immediately after I got married. However, I did not get any oocyte that could be used for my IVF treatment after several times doing the OPU (Oocyte pick-up) surgeries. After all of these treatments, I decided to do IVA (In Vitro Follicle Activation) test to know how many oocytes that I still have. The final test result is that I do not have any oocyte or follicle in my ovarian, and it also means that I don’t have any opportunity to use my own egg having a baby. Therefore, using an oocytes bank is my new hope to have a baby.

At first, we did some research online. My husband and I only found information on oocytes bank in the U.S., but price of these treatments were way too high than we originally expected. In the same time, my original clinic in Japan recommended us to go fertility center in Taiwan. After couple days discussion, my husband and me realize that we could do the oocyte bank in Taiwan, and the price of oocyte bank in Taiwan is more affordable than if we go to the U.S.. Also, the distance from Japan to Taiwan is much closer than from Japan to The U.S.. My original clinic in Japan introduced us to two fertility centers in Taiwan. At First, my husband and I had hard time to make a choice for these two fertility centers in Taiwan, so we e-mailed both of them in the same time. These two fertility centers were replied our question kindly and quickly. Eventually, we choose Stork Fertility Center because most Taiwanese to go here to do IVF or do oocyte bank. Even though another fertility center is more famous in Japan and we can find a lot of information online, we still believe that only local people know these fertility centers better than foreigners like us who from Japan.
   
In the beginning of September, we went to Stork fertility center first time. We took bus from Taiwan Taoyuan International Airport to High Speed Railway Taoyuan station for 15 minis, and we spend another 10 minis for taking High Speed Railway from Taoyuan to Hsinchu. The last step is that Taking a Taxi from High Speed Railway  Hsinchu station to Stork fertility center for 15 minis. When we arrived stork fertility center, and we saw a giant and elegant building in front of our face. If people do not know this building is a fertility center, people may think this building is an art museum. This how amazing that building is. Also, their staffs open the door for you, when you into lobby. I never see any clinic has this kind of service which is like you check in to a hotel.

Finally, we saw the person who was kept sending email with me is our Japanese consulter, Celine. She is a woman who looks very kind and outstanding. She helped us to figure out how to arrange some instruments of law for applying to the oocyte bank, and went to bank to exchange money. The most important thing is that stork fertility center will pay all of the taxi fees for their customers. Also, we have to exchange a large amount of money. It really makes feel safer and sweet that Celine can go to the bank with us. Especially, she found a bank which had a better exchange rate for Japanese to Taiwan currency. When we finished all of paper work for some instruments of law, we still had couple hours waiting for our first visit with deputy superintendentsur. Thus, Celine asked us if we want to have a dinner first, then she print out a map to us, and recommend us a famous local restaurant. Although this restaurant can’t speak Japanese, it still was a great experience to have such tasty food and experience Taiwanese culture.

The deputy superintendent in Stork fertility center can’t speak Japanese, but the first visit with deputy superintendent still was great because Japanese consulter will help translate very thing what deputy superintendent said to us. The Deputy superintendent patiently answer our questions and told to my husband and I that “ I think you will have your baby this year”. This sentence really cheers me up a lot, and helps me use a positive attitude to face the unknown future. Moreover, I noticed that the equipment are better and newer than Japan clinic during the tests. After these tests, we told our conditions to Japanese consulter because under reproductive law in Taiwan, oocyte receiver can’t know how oocyte donor look or any information of this oocyte donor.

When we got all of paper work and tests done, and there were a lot of Taiwanese patients in the waiting area. I recognized that no matter what country you go, there are always a lot of people who have infertility problems. Also, we make sure that the Stork fertility center is very famous and popular in Taiwan. Before we left Stork fertility center, my husband and I went to visit their room which is for foreigners. It is very clean and cozy, just like a deluxe hotel. It’s price for one night also a little bit high as well. Stork fertility center also help us to find a taxi to go Hsinchu train station, and we do not have to pay any fee for this ride.

After we back to Japan one month later, we received a message that they found a oocyte donor from Stork fertility center. However, this donor is not too fit with our expectation, so we decided do a one more round for pair up a new donor. Two weeks later, they found another donor for us, and my husband and I agreed with this donor. Therefore, this all pair process only took around one and half month. This is much faster than I thought. In the end of November, oocyte donor complete OPU (Oocyte pick-up) surgery. During this time, Celine kept updating every single detail of that oocyte bank process. Sometimes, I asked something is not that relate to this oocyte bank, Celine still answered my question very soon and accurate.

The Day Came that I do BT(Blastocyst Transfer). The Deputy Superintendent showed me the photo of that blastocyst before we start to do that surgery,and He told me that the process of thaw blastocyst is good. A minute later, Deputy Superintendent said this BT(Blastocyst Transfer) is going very well, and I still can’t believe that how soon that deputy Deputy Superintendent complete this surgery. Then they moved me to a quiet room for recover, and the staff also prepare a meal as my lunch. It really makes me feel warm and sweet. Two later, I did the blood test in Japan clinic told me that you are pregnant. From the first visit to I'm pregnant, my husband and me only spend four months. I would never believe everything will be that easy to happen.

After 10 months and 10 days, I have my own child, and my family. Even though I took a lot of convoluted path before I want to Stork fertility center, I hug my lovely daughter now. Before I see my daughter, I was worried about my daughter is not look like me. If she is not look like me, do I still love her without any question? However, I see my daughter at first sight. I know these worries are not necessary. I certainly sure I will love her, my daughter forever. Thanks so much to Stork Fertility center for bringing this amazing happiness to me, and also thanks Celine who is our Japanese consulter during this time. Choosing Stork fertility center is the most important choice in my life, and it is the most correct one as well.

Stork Fertility Center送子鳥 Stork Fertility Center送子鳥 Author

Female Premature ovarian failure


Modern people have the phenomenon of late marriages and late child-birth. For a woman, the age is the biggest factor affecting fertility. The older women are, the poorer oocytes quality they have. Not only the fertilization rate, blastocyst implantation rate, pregnancy rate, but also even if they are pregnant, their abortion rate, fetal chromosomal abnormality rate, risk of delivery, are higher than younger women. Through medical tests and examinations, we can know our ovarian function in advance, and let women who are on the journey of having babies to know their own natural conception rate.

Is there any way to know if our ovary is aging and how do we know if our ovarian function is aging?
There are several ways of testing and examining in medicine science that can be predicted in advance.
Below are some ways of evaluating the ovarian function

Follicle-Stimulating Hormone, FSH
FSH is a gonadotropin, a glycoprotein polypeptide hormone. It is synthesized and secreted by the gonadotropic cells of the anterior pituitary gland, and regulates the development, growth, pubertal maturation, and reproductive processes of the body.

Reference
1. Having the blood test on the first day to third day of our period, and it can be used as an indicator to evaluate the "ovarian reserve".
2. This indicator has great variability, and it is recommended to continuously evaluate 2~3 cycles for reference.
3. The reference of values is reduced for who have the ovarian surgery or endometriosis  .


When FSH is above than 10, it is more predictive.
However, 75% of women's ovarian reserve has declined, and this hormone is still within the normal range.
Once it is detected that this hormone has risen, it is usually too late.



Anti-Mullerian Hormone, AMH
AMH is expressed by granulosa cells of the ovary during the reproductive years. It declines with age and oocytes. Due to its high sensitivity, stability and low volatility, it has become the most important indicator for assessing the ovarian reserve.

Reference
1. As the age increases or ovarian reserve begins to decline, AMH will become lower and lower.
2. It is low volatility that we can have the blood test in any day.
3. Combining with FSH and AFC allows, it's more accurate for assessing the ovarian reserve.
4. On average, AMH has declined to 50% when women aged from 30 to 37. However, FSH has only slightly increased. (AMH sensitivity is better than FSH)
5. AMH is associated with the number of retrieval oocytes, fertilization rate, blastocyst quality, pregnancy rate, and abortion rate when doing In Vitro Fertilization (IVF).

 


Inhibin B,
Inhibin B is a sensitive marker of ovarian follicle development and produced by granulosa cells in the ovary, is a heterodimeric glycoprotein suppressing synthesis and secretion of the follicle stimulating hormone (FSH). If the inhibin B on the third day of the period is less than 45 (pg/ml), it means that the ovary may not well respond to ovulation drugs. This hormone has great variability in the period, and it is recommended to evaluate on the second day to the third day of menstruation.

Antral Follicle Counts, AFC
At birth, a female fetus has 1 to 2 million immature eggs called oocytes inside her ovaries, which are all the eggs she will ever produce. By the time a girl enters puberty, about 200,000 of these eggs remain. Approximately 300 to 400 of the remaining eggs will be ovulated during a woman's reproductive lifetime.There is quantitative eggs are screened out in every cycle, but when it is ovulating, only one egg will win, and the other eggs will automatically apoptosis. Therefore, when the menstrual cycle comes, the number of follicles in the ovary can be checked by the transvaginal ultrasound. If the total amount of follicles on both sides is less than 4, it means that the amount of ovarian reserve is not much, which can be clinically correlates with AMH.

However, don't just trust the clinical values, because these indicators or the results of the test only present the status of the current ovarian function, rather than predicting the outcome of pregnancy. As long as we grasp the prime time of pregnancy and do not give up easily, I believe that the happiness in the future will not be too far away. 





Register : Registration Form
Website:www.e-stork.com.tw
Facebook:e-Stork FB Page

LINE ID:storkcryo
Stork Fertility Center送子鳥 Stork Fertility Center送子鳥 Author

IVF Journey x Blastocyst Accumulation


Accumulating Oocytes or Blastocysts for Low Responders? Age as a Criterion.
Several studies have shown maternal age as a determining factor in IVF treatment. 

Most of our patient are suffered from diminished ovarian reserve and/or advanced maternal age. For women over 38-year-old, with declined ovarian reserve, accumulating blastocysts is the strategy we use. Both the quality and quantity of oocytes are adversely affected by the age. They may experience repeated IVF failure caused by few or no embryos to transfer. In this cohort, accumulating blastocysts could be used to increase the chance of pregnancy.  


What is oocytes accumulation? What is blastocysts accumulation?

Oocytes accumulation aimed at collecting oocytes, and freeze it. After we had collected enough oocytes, we thaw all oocytes and fertilize and culture them in one batch. 

Blastocysts accumulation aimed at creating blastocysts and freeze it. After each oocyte retrieval surgery, we fertilize the eggs and culture till day 5~6 then freeze it. 












The clinical outcomes of different age using different treatment shown. 


The result indicated that in using oocytes accumulation, the pregnancy rate of the patient over 38 y/o is 2-3 times less than the patient below 38 y/o.
But the pregnancy rate of oocytes or blastocyst accumulation did not show a significant difference.

To conclude, for age under 38y/o, the pregnancy rate can be reached around 50~70% regardless of what treatment is used; however, forage over 38y/o, the pregnancy rate will be double using blastocyst instead of oocyte 
the pregnancy rate of age over 38y/o is nearly double that of the ovulation pregnancy rate.


How many blastocysts should I collect?

Without pre-implantation genetic screening(PGS), the basis for embryo implantation can only be judged by the developmental speed and appearance level.
Therefore, the pregnancy rate and live birth rate vary with age.
The estimated fee for both treatments is as follow.


To increase the pregnancy rate and live birth rate furthermore,  we introduce you the Third generation IVF Plus( PGS + ERA) . For further require, please contact us  


Leave a message down below, we are more than willing to answer!


Register : Registration Form

WhatsApp:+886-905-737-501 LINE ID:storkcryo

Stork Fertility Center送子鳥 Stork Fertility Center送子鳥 Author

Escape from Death Penalty, Born Again with Oocyte Donation

Finally, it's my turn to write my appreciation letter to Stork Fertility Center. My husband and I have been married for 8 years. We tried many ways to have a child for 7 years. It’s not easy for us to pray for our own child. it’s a long journey.

In the beginning, whoever introduced the doctors to me, I would go if they could help me to get the baby. But the Chinese medicine doctor always told me that my body was too cold to be pregnant. The treatment I got was herbal medicine and acupuncture…etc. However, it did not help me become healthier. My endometrial growths got bigger over time instead. Therefore, I did the three-times of Laparoscopic Surgery. After that my AMH level dropped to 0.16, which means I don't have many eggs in my ovary. Even so, I would never give up. I have a wonderful husband and I love him so much. I want to give him a baby. I will keep trying till last minute.

During the treatment, I have been pregnant four times, but none of them have been grown up. I was so sad and disappointed with myself. I started asking why I could not keep my baby. I did everything I could do and what did I do wrong. I did all the medical inspection, but no one could tell me why I couldn’t get pregnant. I even went to see the doctor of immune dysfunction. The doctor told me the report showed all data looked good. But the devil is still hidden in the details.

All the doctors couldn’t find my problem of infertility. I felt like I have been pronounced with death penalty. I really don't want to give up. Fortunately, I saw the commercials of Stork Fertility Center. It rekindled my hope. I would like to give myself another chance. I told myself if it failed again, at least I tried. Since then I started another journey for having baby.

My Attending Doctor of Stork Fertility Center is Dr. Lai. Because I have already (lost) many times in IVF treatment, and I lost my confidence. But Dr. Lai is so confident and gave me a lot of positive vibes. He told me what he wanted was "success rate". Dr. Lai is a very good doctor. I could feel his attentive and aggressive heart when he did inquiry. It was so touching, so I cried in the clinic room. I only did one IVF treatment in Stork, and I have pregnant. Moreover, doctor help me to transfer to another hospital, for checking my immune dysfunction. In order to ensure I won't lose my baby again.
Ten months pregnant period, I am finally holding my baby. Thanks Dr. Lai gave me a healthy child and made me dream come true.  By Looking at my baby, it reminds me the session of Crescent Moon- The Beginningfrom Rabindranath Tagore...

Your tender softness bloomed in my youthful limbs, like a glow in the sky before the sunrise. 
Heaven's first darling, twin-born with the morning light, you have floated down the stream of the world's life, and at last you have stranded on my heart. 
As I gaze on your face, mystery overwhelms me; you who belong to all have become mine. 
For fear of losing you I hold you tight to my breast. What magic has snared the world's treasure in these slender arms of mine?" 
Rabindranath Tagore
Crescent Moon- The Beginning

Thanks Doctor Lai, thanks Stork Fertility Center, and thanks all the miracle.

 Website:www.e-stork.com.tw

 Facebook:e-Stork FB Page E-mail:en_service@icryobank.com WhatsApp:+886-905-737-501 LINE ID:storkcryo
Stork Fertility Center送子鳥 Stork Fertility Center送子鳥 Author