Showing posts with label sperm quality. Show all posts
Showing posts with label sperm quality. Show all posts
Azoospermia is not a big deal.
5/01/2018 12:00:00 AM
Azoospermia is a severe male factor in the infertility, and the occurrence is around 15% in the infertile men. There are two types of azoospermia,—obstructive and non-obstructive.
Meanwhile, we can classify Azoospermia
more detail into three major types as listed.
1. Non-obstructive
2. Hormone deficiency
3. Testicular failure
Literally, non-obstructive azoospermia refers to no sperm in
the semen because of abnormal sperm production.
The fertility specialist generally recommended these patients
to take microsurgical epididymal sperm aspiration (MESA) or testicular sperm
extraction (TESE) combing with intracellular single
sperm injection (ICSI) in the
IVF program.
How to do the MESA/TESE?
Under regional anesthesia, we would cut apart the scrotum and use a surgical microscope to open the small tubes within the epididymis to look for mature sperm or immature sperm cells. The sperm harvested can be used immediately or frozen for use at a later time. If no sperm are found in epididymis, it is necessary to look inside the testicle for viable sperm.
Usually, the number of sperm retrieved is small and poor activity. Therefore, it
is very precious. It is best to use intracellular single
sperm injection (ICSI) to increase the fertilization rate. The remaining sperm can be frozen
for future use.
This is the most effective
solution to solve azoospermia retrieving sperm.
Also, with the Vitrification, it can be used several times at a time to
achieve maximum benefit.
Through MESA/TESE and
ICSI, it helps to increase the fertilization rate by approximately 70%. About
the pregnancy rate, it’s the same as normal in vitro fertilization which is
50%-60%.
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WhatsApp：+886-905-737-501Traps from delicious foods? Eat right and have better sperm
12/15/2017 01:45:00 AM
Do you
like wearing a tight pants or putting your laptop on your thighs? These habits
may affect the quality of your sperm. Besides, five types of drinks/foods may
harm your reproductive system. Let’s check and keep in mind!
According
to <<Epicurious>>, if the
quality of your sperm is not good, it may affect your family plan. To maintain the good quality of sperm, the
uptakes of following drinks/foods must be controlled.
Alcohols dehydrates the water in our bodies, and increases the risk of
obesity, and reduces the mobility of sperms. We suggest not drinking alcohol
more than once per week, and therefore the bodies can metabolize the alcohol. But
if you have severe reproductive problem, it is better to quit alcohol.
2. Processed meat products
Bacon, ham and burger are delicious, but these processed meat products
usually contain high proportion of saturated fat and hormone residues, which
harm the quality of sperm. If you like meat, have the “fresh” one.
3. Sweet Drinks
Bubble milk tea or other sweet drinks contain high proportion of sugar
stimulating pancreas to release more insulin, and they increases the risk
of obesity. Sweet drinks reduce both the quantity and quality of sperm.
It’s better for us to drink water.
4. High-fat dairy products
Milk, cheese and other dairy products can provide protein, calcium and
other nutrients. But the high fat contained in these products may harm male’s reproductive
system. Also, pesticide or hormone residues should be concerned in some dairy
products.
5. Fruits with pesticide residues
Some of the fruits or vegetables may have pesticide residues, especially
apples, grapes, strawberries, spinach, cucumbers, etc. We suggest choosing
organic fruits and vegetables to decrease the risk.
Stay away from bad habits and unhealthy
foods/drinks. Get your sperm good!
Register：Oversea Form Facebook：e-Stork FB Page E-mail：en_service@icryobank.com WhatsApp：+886-905-737-501What should we know about male infertility
9/30/2017 01:11:00 AM
Like the infertility issues in females,
male fertility correlates with the age, lifestyle, and individual background.
If you are aware of these factors,
you may know more about your own body state.
1. Should semen analysis be routinely clinical testing?
Reproductive potential gradually declines with advanced paternal age, but the declining speed is not as fast as maternal ovaries. The semen analysis is the most common method to check the general sperm quality. Some studies indicated that there is significant decrease in semen volume, sperm concentration, sperm motility and sperm morphology among older men. The pregnancy rate in the men at 40s displayed 10% down than that in the men at 30s. Thus the males with advanced age and abnormal semen parameters have higher risk for the infertility issue. Should the semen analysis be routine testing? Maybe NOT. Only the couple who has failed to conceive for ≧1 year is recommended.
2. Should PGS (preimplantation genetic screening) be performed in the men at advanced age?
The rate of aneuploid embryo is higher in women at advanced age (≧36 years old), and thus PGS becomes an option for them to choose the embryo with normal chromosomal dosage. Is it possible that the aneuploid embryo derived from the sperm with advanced paternal age ? Hassold et al. demonstrated that one of the cause for trisomy 21 is paternal chromosome nondisjunction, and it accounted for 20% of the entire population with trisomy 21. A more-recently scientific article showed that significantly increasing aneuploid rate in embryos from the older men and men with oligozoospermia. It appears that suboptimal sperm can be a source of embryo aneuploidy. However, the correlation of paternal age and embryo aneuploidy is not as strong as that of maternal age. For those with partner at advanced maternal age, or with the recurrent miscarriage history or family inherited disease, PGS/PGD is recommended. Generally, the paternal age is not the sole indication for PGS.
3. What should the older father know?
Several reports showed the children with older fathers are more likely to develop certain pathologies, such as the schizophrenia. The rate of autism spectrum disorders slightly increases as well. For the father themselves, some medical comorbidities do affect the fertility, like heart disease and chronic medicines of hypertension. It could lead to erectile dysfunction and benign prostatic hypertrophy.
4. Should males cryopreserve their sperm for social reason?
The sperm motility could be halved after cryopreservation. For men with known fertile issue, cryopresevation may induce sperm DNA damage. Since the correlation between fertility and male age is not as strong as the female age, there is no need to cryopreserve sperm for the social reason, and the state of frozen sperm is not comparable to the fresh sperm.
Beyond examinations, healthy diet and lifestyle do help the fertility. It's not necessary to cryopreserve sperm at young age. If the body stays good, the quality of sperm may remain for a long time.
Hyaluronan(HA) binding assay: a good matchmaker to sperm
12/08/2016 05:27:00 PM
For in-vitro fertilization, the oocytes attract
the sperms with better maturation status by hyaluronic acid of the surrounding
cumulus cells.
In the 2016 annual meeting of Taiwan Society of Reproductive Medicine, Dr. Dionisios Sakkas from Boston IVF center, US, shared his experiences in semen processing and sperm selection,
1. Density：Gradient separation
2. Surface Charge：Electrophoresis
3. Morphological Characteristics: IMSI (intracytoplasmic morphologically-selected sperm injection)
4. Motility Characteristics： Microfluidics
5. Membrane Integrity：Hyaluronan(HA)-binding
Are you afraid of testicular sperm extraction (TESE)?
9/02/2015 08:14:00 PM
Before starting the IVF program, the diagnostic microdissection testicular sperm extraction can improve the success rate of surgical sperm extraction on the oocyte retrieval day. It would be a great news in the couples with azoospermia.
Should I use Intracytoplasmic Sperm Injection (ICSI)? (ICSI in Taiwan)
1/14/2014 08:30:00 PM
Due to the changes of global climate and general living style, the quality of male sperm, including the morphology and the mobility, has become worse and it also decreased the fertilization rate in the IVF realm. Nowadays, intracytoplasmic sperm injection is the most common technique at ART labs ...
(Source: http://www.goivf.com/treatment-options/ivf-process/male-factor-icsi-tese/ )
Traditional treatments to the fertility problems caused by male factors were limited before 1992. It takes about 74 days to generate mature sperms at testes, so these male patients also needed to take such the same time to receive stimulation injections or oral medications. Thus their patience and perseverance were really the challenges to whom were eager to be fathers. Things were dramatically changed in 1992. Belgium doctor, Dr. Gianpiero Palermo, successfully fertilized the oocytes through Intracytoplasmic Sperm Injection (ICSI) and brought all the IVF patients to another milestone.
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What is Intracytoplasmic Sperm Injection?
ICSI is to inject a single sperm with good shape and mobility into a mature egg (MII oocyte). Though this technique is developed for those with poor quality of sperms, it has become very popular for general IVF cases recently. Then many people may have the question about the appropriate conditions to use ICSI.