Why do I have miscarriages over and over again?
11/25/2018 04:22:00 PM
Being pregnant can be as a duck takes to
water, however for many people, it can be easily achieved, but how to "safely
reach full-term" seems to be a challenge that is harder than climbing up
to the sky.
"Why do I have miscarriages over and
over again?"
After having the examination, we found out
that some mothers have problems with the immune system that is easy to attack
the blastocyst and cause the miscarriage.
The process of pregnancy is a well-designed
by the God. The reason why the blastocyst isn’t attacked by the immune system
is mainly the barrier formed by the placenta between the fetus and the mother, which
can make the immune system unable to identify the fetus as a foreign substance.
Through the effect of hormones, the
blastocyst can peacefully coexist with the mother. The mechanism involved in
the process is very complicated. As long
as one of them goes wrong, it will destroy the mechanism and allowing the
immune system to produce antibodies against the blastocyst during pregnancy. Usually
this immunoreaction may be normal before pregnancy.
Once pregnant, the defense mechanism begins to be so problematic that the blastocyst cannot continue implanting and cause abortion.
Once pregnant, the defense mechanism begins to be so problematic that the blastocyst cannot continue implanting and cause abortion.
In general, there are many autoimmune
diseases have a strong relationship to habitual abortion such as Antiphospholipid
syndrome (APS), Systemic Lupus Erythematosus (SLE), Thrombotic Thrombocytopenic
Purpura (TTP) and so on.
Due to the problem of the immune system, it is easy to form the thrombus, block up the blood vessels of the placenta, and cannot supply nutrients to the fetus. Or it can cause the placenta itself to become inflamed, produce antibodies to attack the blastocyst and lead to abortions.
Due to the problem of the immune system, it is easy to form the thrombus, block up the blood vessels of the placenta, and cannot supply nutrients to the fetus. Or it can cause the placenta itself to become inflamed, produce antibodies to attack the blastocyst and lead to abortions.
In recent years, it has been discovered that there is an immunocyte in the mother's body called "natural killer cell (NK cell)". Under normal conditions, this immunocyte which is produced by the bone marrow in the blood plays the first line of defense to protect the human body. Induced by the thymus gland, it can attack foreign bacteria and viruses, or kill tumor cells. In addition to the NK cells in the blood, there are NK cell also existed in the uterus. Basically, the NK cells in the uterus are different from the one in the blood. It can not only avoid inflaming but also having considerable benefits for implantation. However, if there are excessive NK cells in the uterus, it may cause infertility or abortion.
Therefore, except for the examination of
immune diseases such as complement system (C3, C4), antinuclear antibody (ANA),
antiphospholipid antibody (APA) and anticardiolipin antibody (ACA), the
concentration of NKcells in the uterus can be included in one of the examination
items for habitual abortion.
As long as the concentration of autoantibodies
in the body is too high, it's necessary to treat with the medication before pregnancy.
The medication is including Aspirin, Steroid, Immunosuppressive drug or Heparin
and some patients are suitable the Immune Globulin and Cancer Immunotherapy.
However, it's still a mystery in the medical field that what reasons cause the immunocyte to attack the blastocyst. Therefore, the immune problems and related treatments still need to be evaluated by professional physicians. To increase the pregnancy rate, it’s necessary to deal with it.
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Thank you,
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