Comparison of the obstetric outcome between fresh and vitrified-warmed blastocyst transfer
Author | Hsing-Hua Lai, Huai-Ling Wang, Wen-Yi Chiang, Shih-Chieh Huang, Ya-Hui Hsu |
Editor | Ya-Pei Pong |
Seminar name | 2011 22th AOCOG |
Keyword | vitrification, blastocyst culture, pregnancy rate, live birth rate |
PDF download | |
Objectives
To evaluate the effects of vitrification and embryo development on
implantation rate, clinical and ongoing pregnancy rates along with live birth
rate.
Methods
- A randomized, retrospective
study
- Fresh and vitrified-warmed
blastocyst transfer (BT)
- Statistical methods: Student t
test and Yate’s continuity corrected χ-square
- Definition:
- Biochemical pregnancy: blood β-hCG > 5mIU/mL
- Clinical pregnancy: gestational
sac observed under ultrasound at 6-8 weeks of pregnancy
- Ongoing pregnancy: pregnant
after 5 months
- Implantation rate: gestational
sac or fetal heart beat (FHB) per transferred embryo
Conclusions
Our
preliminary data suggested that:
1.
Vitrification
had no obvious adverse effect on embryos. In fact, it could be beneficial to
increase cumulative pregnancy rate.
2.
The
implantation rate and pregnancy rate after D6 BT were both lower than D5 BT,
implying the importance of embryo growth rate.
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